Photobiomodulation · 650–850 nm

Is photobiomodulation therapy safe?

A significant and growing body of literature indicates that PBMT is safe and effective, and may even improve overall survival in cancer patients. Research continues to answer the open questions about its use in oncology.

About PBM

From the first Nobel Prize to MeSH

Photobiomodulation (PBM) describes the scientific basis of this photonic speciality, and photobiomodulation therapy (PBMT) its therapeutic use.

Phototherapy won the first of many Nobel Prizes in this field in 1903. The first laser was built in 1960, and in 1967 it led to the first documented case of accelerated healing, in veterinary medicine. By the early 1970s laser therapy was recognised as a physical therapy in Eastern Europe and China.

Early on the field used many inconsistent names: biostimulation, cold or cool laser, low‑level laser therapy (LLLT), soft laser, low‑power laser therapy. The current consensus is to use PBM and PBMT.

In 2015, thanks to the efforts of Dr. Praveen Arany, PBMT was added to the U.S. National Library of Medicine MeSH database as an entry term under “laser therapy, low‑level”.

Research database

The PBM database by Vladimir Heiskanen

Vladimir Heiskanen (Valtsu) maintains an extraordinary, freely available database of photobiomodulation research. At our last count it held:

500+randomized studies on humans
223+of them double‑blind
82+of them single‑blind
1170+animal studies
800+rat studies
220+mouse studies
130+systematic reviews
54+meta‑analyses
Open the database
Screenshot of the PBM research database spreadsheet.
“LLLT or PBMT is used to stimulate wound healing, bone fractures or tendon ruptures, spinal cord injuries, traumatic brain injuries, and to reduce pain.”